Primary broth clarification is carried out by a variety of methods ranging from centrifugation to filtration. Today’s ingredient manufacturers are looking for the most cost-effective clarification solutions that will provide the highest product quality and maximum yield, while ensuring process safety and minimizing waste volumes. Unlike centrifugation, where cell size and density as well as fluid viscosity influence the separation efficiency, membrane separation offers an absolute physical barrier that will always provide the optimum separation. GMS has supplied such plants for Italian customers.